Yuki Misawa Selected Research

Galanin Receptors (Galanin Receptor)

1/2019	Promoter methylation of galanin receptors as epigenetic biomarkers for head and neck squamous cell carcinomas.
6/2018	Epigenetic inactivation of galanin receptors in salivary duct carcinoma of the parotid gland: Potential utility as biomarkers for prognosis.
2/2016	Epigenetic inactivation of galanin and GALR1/2 is associated with early recurrence in head and neck cancer.
8/2015	G-Protein-Coupled Receptors: Next Generation Therapeutic Targets in Head and Neck Cancer?
1/2015	Aberrant methylation inactivates somatostatin and somatostatin receptor type 1 in head and neck squamous cell carcinoma.
1/2014	Tumor suppressor activity and inactivation of galanin receptor type 2 by aberrant promoter methylation in head and neck cancer.
6/2013	Galanin has tumor suppressor activity and is frequently inactivated by aberrant promoter methylation in head and neck cancer.
4/2009	Galanin receptor subtype 2 suppresses cell proliferation and induces apoptosis in p53 mutant head and neck cancer cells.

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Yuki Misawa Research Topics

Disease

30	Squamous Cell Carcinoma of Head and Neck 01/2022 - 12/2008
23	Neoplasms (Cancer) 01/2022 - 11/2002
17	Head and Neck Neoplasms (Head and Neck Cancer) 08/2020 - 12/2008
9	Carcinogenesis 08/2020 - 01/2012
4	Oropharyngeal Neoplasms 09/2020 - 01/2015
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 07/2019 - 04/2009
3	Carcinoma (Carcinomatosis) 01/2019 - 11/2002
2	Neoplasm Metastasis (Metastasis) 01/2016 - 11/2002
1	Genomic Instability 01/2020
1	Facial Paralysis (Facial Palsy) 06/2018
1	Mouth Neoplasms (Oral Cancer) 01/2018
1	Hypopharyngeal Neoplasms 01/2018
1	Laryngeal Neoplasms (Laryngeal Cancer) 01/2018
1	Small Cell Carcinoma 05/2016
1	Breast Neoplasms (Breast Cancer) 01/2016
1	Papillomavirus Infections 01/2016
1	Lymphatic Metastasis 03/2014
1	Disease Progression 03/2014
1	Adenocarcinoma 04/2012

Drug/Important Bio-Agent (IBA)

19	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2012
9	GalaninIBA 06/2018 - 04/2009
8	Galanin Receptors (Galanin Receptor)IBA 01/2019 - 04/2009
5	Messenger RNA (mRNA)IBA 08/2020 - 03/2014
5	Proteins (Proteins, Gene)FDA Link 08/2020 - 08/2015
3	Circulating Tumor DNAIBA 01/2022 - 01/2020
3	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 09/2020 - 08/2015
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 11/2018
3	alpha2 Subunit Collagen Type IIBA 01/2018 - 01/2012
3	somatostatin receptor type 1IBA 01/2018 - 01/2015
3	Cyclin D1IBA 08/2015 - 12/2008
3	Tachykinin Receptors (Tachykinin Receptor)IBA 08/2015 - 05/2013
2	5-hydroxymethylcytosineIBA 01/2021 - 01/2019
2	ElementsIBA 01/2020 - 05/2016
2	Biological ProductsIBA 01/2020 - 06/2018
2	Neuropeptide Receptors (Neuropeptide Receptor)IBA 01/2020 - 09/2017
2	Indicators and Reagents (Reagents)IBA 07/2017 - 11/2002
2	Type 1 Galanin ReceptorIBA 01/2017 - 12/2008
2	Cadherins (E-Cadherin)IBA 05/2016 - 05/2013
2	H-cadherin (T-cadherin)IBA 05/2016 - 01/2012
2	Type 2 Galanin ReceptorIBA 09/2014 - 01/2014
2	CollagenIBA 03/2014 - 01/2012
1	Opioid Receptors (Opioid Receptor)IBA 01/2022
1	ORALIT (ORS)IBA 01/2022
1	Transcription Factors (Transcription Factor)IBA 08/2020
1	Small Interfering RNA (siRNA)IBA 08/2020
1	DNA Methyltransferase 3AIBA 08/2020
1	NucleotidesIBA 01/2020
1	ProstaglandinsIBA 01/2020
1	Retroelements (Retrotransposon)IBA 01/2020
1	EnzymesIBA 01/2019
1	DioxygenasesIBA 01/2019
1	Hormones (Hormone)IBA 06/2018
1	human ERBB2 proteinIBA 06/2018
1	NeuropeptidesIBA 01/2018
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 07/2017
1	Aromatase InhibitorsIBA 01/2016
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2015
1	cytidylyl-3'-5'-guanosineIBA 01/2014
1	Annexin A5IBA 04/2009
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 11/2002
1	Glucose (Dextrose)FDA LinkGeneric 11/2002

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 11/2018 - 01/2016
2	Therapeutics 06/2018 - 04/2009
1	Laryngectomy 05/2016
1	Neck Dissection (Radical Neck Dissection) 05/2016
1	Mastectomy (Mammectomy) 01/2016
1	Pancreatectomy 04/2012
1	Pancreaticoduodenectomy 04/2012